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The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
This reagent has been pre-diluted for use at the recommended Volume per Test. Please refer to www. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions.
Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
For fluorochrome spectra and suitable instrument settings, please refer to our Multicolor Flow Cytometry web page at www.
This product may be covered by US Patent No. An isotype control should be used at the same concentration as the antibody of interest.
The Qing imperial resident, known as the Amban , publicly repudiated the treaty, while the British government, eager for friendly relations with China, negotiated a new treaty two years later known as the Convention Between Great Britain and China Respecting Tibet.
The British agreed not to annex or interfere in Tibet in return for an indemnity from the Chinese government, while China agreed not to permit any other foreign state to interfere with the territory or internal administration of Tibet.
In , the Qing government sent a military expedition of its own under Zhao Erfeng to establish direct Manchu-Chinese rule and, in an imperial edict, deposed the Dalai Lama, who fled to British India.
Zhao Erfeng defeated the Tibetan military conclusively and expelled the Dalai Lama's forces from the province. His actions were unpopular, and there was much animosity against him for his mistreatment of civilians and disregard for local culture.
After the Xinhai Revolution —12 toppled the Qing dynasty and the last Qing troops were escorted out of Tibet, the new Republic of China apologized for the actions of the Qing and offered to restore the Dalai Lama's title.
During this time, Tibet fought Chinese warlords for control of the ethnically Tibetan areas in Xikang and Qinghai parts of Kham and Amdo along the upper reaches of the Yangtze River.
The Chinese government denounced the agreement as illegal. When in the s and s the regents displayed negligence in affairs, the Kuomintang Government of the Republic of China took advantage of this to expand its reach into the territory.
Emerging with control over most of mainland China after the Chinese Civil War , the People's Republic of China incorporated Tibet in and negotiated the Seventeen Point Agreement with the newly enthroned 14th Dalai Lama 's government, affirming the People's Republic of China's sovereignty but granting the area autonomy.
Subsequently, on his journey into exile, the 14th Dalai Lama completely repudiated the agreement, which he has repeated on many occasions.
The Dalai Lama had a strong following as many people from Tibet looked at him not just as their political leader, but as their spiritual leader.
Afterwards, the Central People's Government in Beijing renounced the agreement and began implementation of the halted social and political reforms.
In , General Secretary and reformist Hu Yaobang visited Tibet and ushered in a period of social, political, and economic liberalization.
The government halted reforms and started an anti- separatist campaign. All of modern China, including Tibet, is considered a part of East Asia.
Tibet has some of the world's tallest mountains, with several of them making the top ten list. Several major rivers have their source in the Tibetan Plateau mostly in present-day Qinghai Province.
Tibet has been called the "Water Tower" of Asia, and China is investing heavily in water projects in Tibet. The mountain is a holy pilgrimage site for both Hindus and Tibetans.
The Hindus consider the mountain to be the abode of Lord Shiva. The Tibetan name for Mt. Kailash is Khang Rinpoche. Tibet has numerous high-altitude lakes referred to in Tibetan as tso or co.
Western passes receive small amounts of fresh snow each year but remain traversible all year round.
Low temperatures are prevalent throughout these western regions, where bleak desolation is unrelieved by any vegetation bigger than a low bush, and where wind sweeps unchecked across vast expanses of arid plain.
The Indian monsoon exerts some influence on eastern Tibet. Northern Tibet is subject to high temperatures in the summer and intense cold in the winter.
Cultural Tibet consists of several regions. These include Amdo A mdo in the northeast, which is administratively part of the provinces of Qinghai, Gansu and Sichuan.
Kham Khams in the southeast encompasses parts of western Sichuan, northern Yunnan , southern Qinghai and the eastern part of the Tibet Autonomous Region.
Tibetan cultural influences extend to the neighboring states of Bhutan , Nepal, regions of India such as Sikkim , Ladakh , Lahaul , and Spiti , Northern Pakistan Baltistan or Balti-yul in addition to designated Tibetan autonomous areas in adjacent Chinese provinces.
There are over settlements in Tibet. Lhasa is Tibet's traditional capital and the capital of Tibet Autonomous Region.
Lhasa contains a number of significant temples and monasteries, including Jokhang and Ramoche Temple. Shigatse is the second largest city in the Tibet AR, west of Lhasa.
Gyantse and Qamdo are also amongst the largest. It is governed by a People's Government, led by a Chairman. In practice, however, the Chairman is subordinate to the branch secretary of the Communist Party of China.
As a matter of convention, the Chairman has almost always been an ethnic Tibetan, while the party secretary has always been ethnically non-Tibetan.
The Tibetan economy is dominated by subsistence agriculture. Due to limited arable land, the primary occupation of the Tibetan Plateau is raising livestock, such as sheep , cattle, goats , camels , yaks , dzo , and horses.
The dogs of Tibet are twice the size of those seen in India, with large heads and hairy bodies. They are powerful animals, and are said to be able to kill a tiger.
During the day they are kept chained up, and are let loose at night to guard their masters' house. The main crops grown are barley , wheat, buckwheat , rye , potatoes, and assorted fruits and vegetables.
These include Tibetan hats, jewelry silver and gold , wooden items, clothing, quilts, fabrics, Tibetan rugs and carpets. Forty percent of the rural cash income in the Tibet Autonomous Region is derived from the harvesting of the fungus Ophiocordyceps sinensis formerly Cordyceps sinensis ; contributing at least 1.
The Qingzang railway linking the Tibet Autonomous Region to Qinghai Province was opened in , but it was controversial. In January , the Chinese government issued a report outlining the discovery of a large mineral deposit under the Tibetan Plateau.
The Chinese government sees this as a way to alleviate the nation's dependence on foreign mineral imports for its growing economy.
However, critics worry that mining these vast resources will harm Tibet's fragile ecosystem and undermine Tibetan culture. On January 15, , China announced the construction of Tibet's first expressway, the Lhasa Airport Expressway , a The project will cost 1.
From January 18—20, , a national conference on Tibet and areas inhabited by Tibetans in Sichuan, Yunnan, Gansu and Qinghai was held in China and a substantial plan to improve development of the areas was announced.
The plan calls for improvement of rural Tibetan income to national standards by and free education for all rural Tibetan children.
It is located in the western suburbs of Lhasa, the capital of the Tibet Autonomous Region. The zone has a planned area of 5.
Zone A developed a land area of 2. It is a flat zone, and has the natural conditions for good drainage.
Historically, the population of Tibet consisted of primarily ethnic Tibetans and some other ethnic groups. According to tradition the original ancestors of the Tibetan people, as represented by the six red bands in the Tibetan flag , are: the Se, Mu, Dong, Tong, Dru and Ra.
The proportion of the non-Tibetan population in Tibet is disputed. On the one hand, the Central Tibetan Administration of the Dalai Lama accuses China of actively swamping Tibet with migrants in order to alter Tibet's demographic makeup.
Religion is extremely important to the Tibetans and has a strong influence over all aspects of their lives. Bön is the indigenous religion of Tibet, but has been almost eclipsed by Tibetan Buddhism, a distinctive form of Mahayana and Vajrayana , which was introduced into Tibet from the Sanskrit Buddhist tradition of northern India.
Monks returned to monasteries across Tibet and monastic education resumed even though the number of monks imposed is strictly limited.
Tibetan Buddhism has five main traditions the suffix pa is comparable to "er" in English :. The Chinese government continued to pursue a strategy of forced assimilation and suppression of Tibetan Buddhism, as demonstrated by the laws designed to control the next reincarnation of the Dalai Lama and those of other Tibetan eminent lamas.
Monks and nuns who refused to denounce the Dalai Lama have been expelled from their monasteries, imprisoned, and tortured. The first Christians documented to have reached Tibet were the Nestorians , of whom various remains and inscriptions have been found in Tibet.
Roman Catholic Jesuits and Capuchins arrived from Europe in the 17th and 18th centuries. These included the Jesuit Father Ippolito Desideri , —, who gained a deep knowledge of Tibetan culture, language and Buddhism, and various Capuchins in —, — and —,  Christianity was used by some Tibetan monarchs and their courts and the Karmapa sect lamas to counterbalance the influence of the Gelugpa sect in the 17th century until in when all the missionaries were expelled at the lama's insistence.
Famous earlier missionaries include James O. Proselytising has been illegal in China since But as of [update] , many Christian missionaries were reported to be active in Tibet with the tacit approval of Chinese authorities, who view the missionaries as a counterforce to Tibetan Buddhism or as a boon to the local economy.
Muslims have been living in Tibet since as early as the 8th or 9th century. In Tibetan cities, there are small communities of Muslims , known as Kachee Kache , who trace their origin to immigrants from three main regions: Kashmir Kachee Yul in ancient Tibetan , Ladakh and the Central Asian Turkic countries.
Islamic influence in Tibet also came from Persia. Which became main cause of the cultural separation of the people of Baltistan from the mainstream Tibet.
After a group of Tibetan Muslims made a case for Indian nationality based on their historic roots to Kashmir and the Indian government declared all Tibetan Muslims Indian citizens later on that year.
There is also a well established Chinese Muslim community gya kachee , which traces its ancestry back to the Hui ethnic group of China.
Tibetan representations of art are intrinsically bound with Tibetan Buddhism and commonly depict deities or variations of Buddha in various forms from bronze Buddhist statues and shrines, to highly colorful thangka paintings and mandalas.
Tibetan architecture contains Chinese and Indian influences, and reflects a deeply Buddhist approach. The Buddhist wheel , along with two dragons, can be seen on nearly every Gompa in Tibet.
The design of the Tibetan Chörtens can vary, from roundish walls in Kham to squarish, four-sided walls in Ladakh. Genetic variations in T-bet are associated with susceptibility to aspirin-induced asthma and nasal polyps.
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PubMed Chen D, et al. PubMed Subramanian K, et al. Nat Microbiol. PubMed Chatterjee S et al. Cell metabolism. PubMed Fu B et al.
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T-bet expression is optimally observed after IL stimulation and can be suppressed by addition of the Th2 cytokine IL-4 or neutralization of IL It is recommended that the reagent be titrated for optimal performance for each application.
Additional reported applications for the relevant formats include: immunoprecipitation 2 and immunofluorescence microscopy 3.
Szabo SJ, et al. Cell Science Finotto S, et al. Mullen AC, et al. For research use only. Not for diagnostic use. Not for resale.
By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses.In general, the dialects of central Game Affe including LhasaKhamRoshtein and some smaller nearby areas are considered Tibetan dialects. From the perspective of historical linguistics, Tibetan most closely resembles Burmese among the major languages of Asia. PubMed Yadava K et al. Main article: History of Tibet. Grove Press. Human amino acids; Standing at metres feet in height and metres 1, feet in width, the Potala Palace is the most important example of Tibetan architecture. Description 200$ In € 4B10 monoclonal antibody specifically binds to human and mouse T-bet. Main article: Tibetan cuisine. It controls the expression of the TH1 Gewinnspiele Kostenlos Geld, interferon-gamma. The plan calls for improvement of rural Tibetan income to national standards by and free education for all rural Wildjack children. Se connecter. As the Qing dynasty weakened, its authority over Tibet also gradually Steve Lennon, and by the midth century its influence was minuscule. Duckduck : Genes on Bayern Gegen Hertha 2021 chromosome 17 Transcription factors Human chromosome 17 gene stubs. Main article: Islam in Tibet. Tibet has numerous high-altitude lakes referred to in Tibetan as tso or co.